<?xml version='1.0' encoding='UTF-8'?><codeBook xmlns="ddi:codebook:2_5" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xsi:schemaLocation="ddi:codebook:2_5 https://ddialliance.org/Specification/DDI-Codebook/2.5/XMLSchema/codebook.xsd" version="2.5"><docDscr><citation><titlStmt><titl>Lysine Deprivation Suppresses Adipogenesis in 3T3-L1 Cells: A Transcriptome Analysis</titl><IDNo agency="DOI">doi:10.60933/PRDR/RWJUCX</IDNo></titlStmt><distStmt><distrbtr source="archive">PolyU Research Data Repository</distrbtr><distDate>2024-06-06</distDate></distStmt><verStmt source="archive"><version date="2024-06-06" type="RELEASED">1</version></verStmt><biblCit>Lee, Leo Man Yuen; Leung, Thomas Yun-chung, 2024, "Lysine Deprivation Suppresses Adipogenesis in 3T3-L1 Cells: A Transcriptome Analysis", https://doi.org/10.60933/PRDR/RWJUCX, PolyU Research Data Repository, V1</biblCit></citation></docDscr><stdyDscr><citation><titlStmt><titl>Lysine Deprivation Suppresses Adipogenesis in 3T3-L1 Cells: A Transcriptome Analysis</titl><IDNo agency="DOI">doi:10.60933/PRDR/RWJUCX</IDNo></titlStmt><rspStmt><AuthEnty affiliation="Hong Kong Polytechnic University">Lee, Leo Man Yuen</AuthEnty><AuthEnty affiliation="Hong Kong Polytechnic University">Leung, Thomas Yun-chung</AuthEnty></rspStmt><prodStmt/><distStmt><distrbtr source="archive">PolyU Research Data Repository</distrbtr><contact affiliation="Hong Kong Polytechnic University" email="man-yuen.lee@polyu.edu.hk">Lee, Leo Man Yuen</contact><depositr>PolyU, Research Data Repository</depositr><depDate>2024-05-30</depDate></distStmt><holdings URI="https://doi.org/10.60933/PRDR/RWJUCX"/></citation><stdyInfo><subject><keyword xml:lang="en">Medicine, Health and Life Sciences</keyword></subject><abstract>Organism: Mus musculus&lt;br>
Summary: It has been reported that low concentration of lysine suppressed lipid accumulation and transcription of several adipogenic genes in 3T3-L1 preadipocytes, however, the detailed lysine deprivation-specific cellular transcriptomic changes and the altered pathways have not yet been fully decrypted.&lt;br>
Overall design: Using 3T3-L1 cells, we performed RNA sequencing on undifferentiated cells, differentiated cells, and differentiated cells under a lysine-free culture medium</abstract><sumDscr/></stdyInfo><method><dataColl><sources/></dataColl><anlyInfo/></method><dataAccs><setAvail/><useStmt/></dataAccs><othrStdyMat><relPubl><citation><titlStmt><titl>Lee, L. M. Y., Lin, Z. Q., Zheng, L. X., Tu, Y. F., So, Y. H., Zheng, X. H., ... &amp; Leung, Y. C. (2023). Lysine Deprivation Suppresses Adipogenesis in 3T3-L1 Cells: A Transcriptome Analysis. International Journal of Molecular Sciences, 24(11), 9402</titl><IDNo agency="doi">10.3390/ijms24119402</IDNo></titlStmt><biblCit>Lee, L. M. Y., Lin, Z. Q., Zheng, L. X., Tu, Y. F., So, Y. H., Zheng, X. H., ... &amp; Leung, Y. C. (2023). Lysine Deprivation Suppresses Adipogenesis in 3T3-L1 Cells: A Transcriptome Analysis. International Journal of Molecular Sciences, 24(11), 9402</biblCit></citation><ExtLink URI="https://doi.org/10.3390/ijms24119402"/></relPubl><relPubl><citation><titlStmt><titl>Link in PolyU Institutional Research Archive (PIRA)</titl></titlStmt><biblCit>Link in PolyU Institutional Research Archive (PIRA)</biblCit></citation><ExtLink URI="http://hdl.handle.net/10397/99463"/></relPubl></othrStdyMat></stdyDscr><otherMat ID="f425" URI="https://researchdata.lib.polyu.edu.hk/api/access/datafile/425" level="datafile"><labl>SRR23252438.sra</labl><txt>Treatment: Adipogenic differentiation+lysine free medium</txt><notes level="file" type="DATAVERSE:CONTENTTYPE" subject="Content/MIME Type">application/octet-stream</notes></otherMat><otherMat ID="f426" URI="https://researchdata.lib.polyu.edu.hk/api/access/datafile/426" level="datafile"><labl>SRR23252439.sra</labl><txt>Treatment: Adipogenic differentiation+lysine free medium</txt><notes level="file" type="DATAVERSE:CONTENTTYPE" subject="Content/MIME Type">application/octet-stream</notes></otherMat><otherMat ID="f428" URI="https://researchdata.lib.polyu.edu.hk/api/access/datafile/428" level="datafile"><labl>SRR23252440.sra</labl><txt>Treatment: Adipogenic differentiation+lysine free medium</txt><notes level="file" type="DATAVERSE:CONTENTTYPE" subject="Content/MIME Type">application/octet-stream</notes></otherMat><otherMat ID="f429" URI="https://researchdata.lib.polyu.edu.hk/api/access/datafile/429" level="datafile"><labl>SRR23252441.sra</labl><txt>Treatment: Adipogenic differentiation</txt><notes level="file" type="DATAVERSE:CONTENTTYPE" subject="Content/MIME Type">application/octet-stream</notes></otherMat><otherMat ID="f430" URI="https://researchdata.lib.polyu.edu.hk/api/access/datafile/430" level="datafile"><labl>SRR23252442.sra</labl><txt>Treatment: Adipogenic differentiation</txt><notes level="file" type="DATAVERSE:CONTENTTYPE" subject="Content/MIME Type">application/octet-stream</notes></otherMat><otherMat ID="f431" URI="https://researchdata.lib.polyu.edu.hk/api/access/datafile/431" level="datafile"><labl>SRR23252443.sra</labl><txt>Treatment: Adipogenic differentiation</txt><notes level="file" type="DATAVERSE:CONTENTTYPE" subject="Content/MIME Type">application/octet-stream</notes></otherMat><otherMat ID="f427" URI="https://researchdata.lib.polyu.edu.hk/api/access/datafile/427" level="datafile"><labl>SRR23252444.sra</labl><txt>Treatment: Undifferentiation control</txt><notes level="file" type="DATAVERSE:CONTENTTYPE" subject="Content/MIME Type">application/octet-stream</notes></otherMat><otherMat ID="f432" URI="https://researchdata.lib.polyu.edu.hk/api/access/datafile/432" level="datafile"><labl>SRR23252445.sra</labl><txt>Treatment: Undifferentiation control</txt><notes level="file" type="DATAVERSE:CONTENTTYPE" subject="Content/MIME Type">application/octet-stream</notes></otherMat><otherMat ID="f433" URI="https://researchdata.lib.polyu.edu.hk/api/access/datafile/433" level="datafile"><labl>SRR23252446.sra</labl><txt>Treatment: Undifferentiation control</txt><notes level="file" type="DATAVERSE:CONTENTTYPE" subject="Content/MIME Type">application/octet-stream</notes></otherMat></codeBook>