<?xml version='1.0' encoding='UTF-8'?><metadata xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:dcterms="http://purl.org/dc/terms/" xmlns="http://dublincore.org/documents/dcmi-terms/"><dcterms:title>Lysine Deprivation Suppresses Adipogenesis in 3T3-L1 Cells: A Transcriptome Analysis</dcterms:title><dcterms:identifier>https://doi.org/10.60933/PRDR/RWJUCX</dcterms:identifier><dcterms:creator>Lee, Leo Man Yuen</dcterms:creator><dcterms:creator>Leung, Thomas Yun-chung</dcterms:creator><dcterms:publisher>PolyU Research Data Repository</dcterms:publisher><dcterms:issued>2024-06-06</dcterms:issued><dcterms:modified>2024-06-06T01:32:42Z</dcterms:modified><dcterms:description>Organism: Mus musculus&lt;br>
Summary: It has been reported that low concentration of lysine suppressed lipid accumulation and transcription of several adipogenic genes in 3T3-L1 preadipocytes, however, the detailed lysine deprivation-specific cellular transcriptomic changes and the altered pathways have not yet been fully decrypted.&lt;br>
Overall design: Using 3T3-L1 cells, we performed RNA sequencing on undifferentiated cells, differentiated cells, and differentiated cells under a lysine-free culture medium</dcterms:description><dcterms:subject>Medicine, Health and Life Sciences</dcterms:subject><dcterms:isReferencedBy>Lee, L. M. Y., Lin, Z. Q., Zheng, L. X., Tu, Y. F., So, Y. H., Zheng, X. H., ... &amp; Leung, Y. C. (2023). Lysine Deprivation Suppresses Adipogenesis in 3T3-L1 Cells: A Transcriptome Analysis. International Journal of Molecular Sciences, 24(11), 9402, doi, 10.3390/ijms24119402, https://doi.org/10.3390/ijms24119402</dcterms:isReferencedBy><dcterms:isReferencedBy>Link in PolyU Institutional Research Archive (PIRA), http://hdl.handle.net/10397/99463</dcterms:isReferencedBy><dcterms:date>2024-06-06</dcterms:date><dcterms:contributor>PolyU, Research Data Repository</dcterms:contributor><dcterms:dateSubmitted>2024-05-30</dcterms:dateSubmitted><dcterms:license>CC BY-NC 4.0</dcterms:license></metadata>